ibuprophen) This fever reducing,
pain relieving, blood thinning compound was introduced in 1974 and is often used where pain relief is needed
without a large anti-inflammatory effect. Ibuprofen is in a class of drugs called nonsteroidal
anti-inflammatory drugs (NSAIDs). Ibuprofen works by reducing hormones that cause
inflammation and pain in the body. Lower doses can control pain but higher doses are needed to treat
inflammation. It is inferior to aspirin as an anti-inflammatory as
it may cause gastrointestinal irritation and the effective dosage is greater. It is an alternative for some
persons, however, who cannot take aspirin, due to ulcers or other stomach maladies.
It should not be taken
with aspirin because the combination can cause further stomach upset and
also cause blood clotting impairment. If you are taking a normal regimen
of aspirin it is not recommended to take ibuprofen. Patients
taking both aspirin and ibuprofen had nearly twice the risk of death from any cause -- and a 73% increased risk
of death from heart disease. There was no increased
numbers of deaths among those taking aspirin with other painkillers similar to ibuprofen.
It's mode of action, like that of other nonsteroidal
anti-inflammatory agents, is not completely understood, but may be related to prostaglandin synthetase
Many athletes take
this compound as part of their normal training routine or prior to major competitions such as marathons.
This popular pain reliever blocks the heart-protecting
effects of aspirin, according to a new study. The results, if confirmed, would have major implications for
millions of people who take a small dose of aspirin every day for their hearts, but who also take ibuprofen,
widely known in North America under the brand names Advil and Motrin, to cope with conditions such as
This particular NSAID has a more potent anti-inflammatory
agent than aspirin. It, then is sometimes more effective for arthritic patients with fewer side effects. Food
does delay the absorption but not the total drug intake. Ibuprofen is effective for mild to moderate pain. It
works much the same as Aspirin. Pain relief should be expected in about 30 minutes.
is effective, also, as an anti-pyretic (reduces fever) much the same as aspirin.
Why to prescribe
Ibuprofen is used to relieve the pain, tenderness, inflammation (swelling), and stiffness caused by arthritis and gout.
It also is used to reduce fever and to relieve headaches, muscle aches, menstrual pain, aches and pains
from the common cold, backache, and pain after surgery or dental work.
The side effects related to Ibuprofen, though fewer in number, can be more intense in symptoms. The most common
side effects are GI (gastrointestinal) in origin. They include complaints of nausea, vomiting, anorexia,
diarrhea, and abdominal pain and occasionally even ulcers of the upper intestinal tract. There are other
possible and less frequent side effects involving the central nervous system, liver and even allergic
reactions like rashes.
use of nonaspirin pain relievers does increase the risk for high blood pressure.
In one groundbreaking study, women who took nonsteroidal anti-inflammatories (NSAIDs),
such as ibuprofen, 22 times a month or more were 86% more likely to have high
blood pressure than those who did not take NSAIDs. Those taking acetaminophen
were twice as likely to be hypertensive. Aspirin did not increase the risk.
experience any of the following serious side effects,
stop taking ibuprofen and seek medical treatment or call your doctor immediately:
* an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or
* muscle cramps, numbness, or tingling;
* ulcers (open sores) in the mouth;
* rapid weight gain (fluid retention);
* black, bloody, or tarry stools;
* blood in your urine or vomit;
* decreased hearing or ringing in the ears;
* jaundice (yellowing of the skin or eyes); or
* abdominal cramping, indigestion, or heartburn.
Chart for Motrin/Advil
(Ibuprofen) Suspension (100mg per tsp):
2 1/2 Teaspoons
3 1/2 Teaspoons
1 1/4 Teaspoons
4 1/2 Teaspoons
1 1/2 Teaspoons
1 3/4 Teaspoons
Dosing is every 6 hours. Take ibuprofen with food, milk,
or an antacid to lessen stomach upset. Take each dose
with a full glass of water. Avoid prolonged exposure to
sunlight. Ibuprofen may increase the sensitivity of the
skin to sunlight. Use a sunscreen and wear protective
clothing when exposure to the sun is unavoidable. If you
drink more than three alcoholic beverages a day, ibuprofen may increase the risk of stomach bleeding.
Store ibuprofen at room temperature away from moisture and heat.
Symptoms of a ibuprofen overdose include nausea, vomiting or stomach pain,
dizziness, drowsiness, headache, ringing in the ears,
blurred vision, seizures, sweating, numbness or
tingling, little or no urine production, and slow breathing.
Note: Manufacturers change their products from time to
time. For this reason, always refer to the manufacturer's information if available.